Protein Information

Name cytochrome b5
Synonyms CYB 5; CYB5; CYB5A; Cytochrome b 5; Cytochrome b5; MCB 5; MCB5; Microsomal cytochrome b5…

Compound Information

Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference List

PubMed Abstract RScore(About this table)
525897 Elissalde MH Jr, Clark DE: Testosterone metabolism by hexachlorobenzene-induced hepatic microsomal enzymes. Am J Vet Res. 1979 Dec;40(12):1762-6.

Significant increases in the mean hepatic weight, the concentrations of hepatic microsomal protein, cytochrome P-450, cytochrome b5, and cytochrome c reductase activity occurred in the aminals given a ration containing 250 mg of hexachlorobenzene/kg for 21 days, when compared with their nontreated controls.
6(0,0,1,1) Details
3629612 Cantoni L, Rizzardini M, Tacconi MT, Graziani A: Comparison of hexachlorobenzene-induced alterations of microsomal membrane composition and monooxygenase activity in male and female rats. Toxicology. 1987 Sep;45(3):291-305.

Cytochrome P-450 was induced more in male than in female animals while cytochrome b5 was induced only in males.
1(0,0,0,1) Details