| Name | prion protein |
|---|---|
| Synonyms | ASCR; PRIP; PRP; PRNP; Prion related protein; CD230; CD230 antigen; CJD… |
| Name | streptomycin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16491180 | Moussa A, Coleman AW, Bencsik A, Leclere E, Perret F, Martin A, Perron H: Use of streptomycin for precipitation and detection of proteinase K resistant prion protein (PrPsc) in biological samples. Chem Commun. 2006 Mar 7;(9):973-5. Epub 2006 Jan 20. |
12(0,0,2,2) | Details |
| 19188908 | Quadrio I, Ugnon-Cafe S, Dupin M, Esposito G, Streichenberger N, Krolak-Salmon P, Vital A, Pellissier JF, Perret-Liaudet A, Perron H: Rapid diagnosis of human prion disease using streptomycin with tonsil and brain tissues. Lab Invest. 2009 Apr;89(4):406-13. Epub 2009 Feb 2. The use of streptomycin in the pathological prion protein (PrP (sc)) detection procedures represents a new and attractive way for diagnostic purpose. |
6(0,0,1,1) | Details |
| 16549507 | Bencsik AA, Coleman AW, Debeer SO, Perron H, Moussa A: Amplified immunohistochemical detection of PrPsc in animal transmissible spongiform encephalopathies using streptomycin. J Histochem Cytochem. 2006 Aug;54(8):849-53. Epub 2006 Mar 20. Due to its sensitivity, immunohistochemistry (IHC) of abnormal prion protein (PrPsc) is used to study experimental and natural cases of transmissible spongiform encephalopathies (TSEs) such as Creutzfeldt-Jakob disease in humans or scrapie and bovine spongiform encephalopathy (BSE) in animals. |
1(0,0,0,1) | Details |
| 18224331 | Bencsik AA, Leclere E, Perron H, Moussa A: New insights into early sequential PrPsc accumulation in scrapie infected mouse brain evidenced by the use of streptomycin sulfate. Histochem Cell Biol. 2008 May;129(5):643-50. Epub 2008 Jan 26. To investigate the amplifying potentialities of streptomycin sulfate in the immunohistochemical (IHC) detection of the abnormal prion protein (PrPsc), we used a sequential brain sampling from C506M3 scrapie strain inoculated C57Bl/6 mice. |
1(0,0,0,1) | Details |
| 17894644 | Dong CF, Huang YX, An R, Chen JM, Wang XF, Shan B, Lei YJ, Han L, Zhang BY, Han J, Dong XP: Sensitive detection of PrPSc by Western blot assay based on streptomycin sulphate precipitation. Zoonoses Public Health. 2007;54(8):328-36. Transmissible spongiform encephalopathies, also termed prion diseases, are fatal neurodegenerative disorders that affect both humans and animals, which are characterized by presences of protease-resistance disease-associated prion protein (PrP (Sc)) in brains. Employs of PrP (Sc) stock sample into various mimic specimens, including normal hamster brain homogenate, human cerebrospinal fluid and urine, demonstrated that streptomycin precipitation markedly increased the detective sensitivity of PrP (Sc), regardless in low concentration or in large volume. |
1(0,0,0,1) | Details |