Protein Information

Name histone deacetylase (protein family or complex)
Synonyms Histone deacetylase; Histone deacetylases

Compound Information

Name thiram
CAS

Reference List

PubMed Abstract RScore(About this table)
19789329 Iljin K, Ketola K, Vainio P, Halonen P, Kohonen P, Fey V, Grafstrom RC, Perala M, Kallioniemi O: High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth. Clin Cancer Res. 2009 Oct 1;15(19):6070-8. Epub 2009 Sep 29.

In contrast, histone deacetylase inhibitor trichostatin A, thiram, DSF, and monensin were identified as selective antineoplastic agents that inhibited VCaP and LNCaP cell proliferation at nanomolar concentrations.
31(0,1,1,1) Details