Protein Information

Name vimentin
Synonyms VIM; Vimentin; Vimentins

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
12211104 Rusanen H, Annunen J, Yla-Outinen H, Laurila A, Peltonen J, Hassinen IE, Majamaa K: Cytoskeletal structure of myoblasts with the mitochondrial DNA 3243A--> G mutation and of osteosarcoma cells with respiratory chain deficiency. Cell Motil Cytoskeleton. 2002 Nov;53(3):231-8.

Vimentin filaments formed large bundles surrounding the nucleus in mtDNA-less (rho (0)) osteosarcoma cells and in osteosarcoma cells after incubation with sodium azide and nocodazole.
7(0,0,1,2) Details
17533645 Annunen-Rasila J, Ohlmeier S, Tuokko H, Veijola J, Majamaa K: Proteome and cytoskeleton responses in osteosarcoma cells with reduced OXPHOS activity. Proteomics. 2007 Jun;7(13):2189-200.


We have recently shown disorganization of the vimentin network in cultured cells deficient in oxidative phosphorylation (OXPHOS).
4(0,0,0,4) Details
14688152 Demir AY, Groothuis PG, Nap AW, Punyadeera C, de Goeij AF, Evers JL, Dunselman GA: Menstrual effluent induces epithelial-mesenchymal transitions in mesothelial cells. Hum Reprod. 2004 Jan;19(1):21-9.

Sodium azide, an inhibitor of ATP production, and Genistein, a general tyrosine kinase inhibitor, antagonized these effects.
The expression of Snail and vimentin was markedly up-regulated, whereas the expression of E-cadherin was decreased and cytokeratins were altered.
2(0,0,0,2) Details