| Name | prothrombin |
|---|---|
| Synonyms | Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin… |
| Name | malathion |
|---|---|
| CAS | diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2356569 | Keadtisuke S, Dheranetra W, Nakatsugawa T, Fukuto TR: Liver damage induced in rats by malathion impurities. Toxicol Lett. 1990 Jun;52(1):35-46. Administration of a single oral dose of the malathion impurity, O,O,S-trimethyl phosphorothioate (OOS-Me) or O,S,S-trimethyl phosphorodithioate (OSS-Me), to the rat resulted in hemostatic disorders, e.g. prolongation of blood clotting, prothrombin and thrombin time. |
6(0,0,1,1) | Details |
| 4067834 | Lox CD: Short term malathion ingestion and blood clotting in the rat. J Environ Pathol Toxicol Oncol. 1985 Sep-Oct;6(1):51-5. Plasma samples were assayed for prothrombin time (PT), partial thromboplastin time (APTT), hematocrit (HCT), platelet count (PLT) and clot activation time for fibrinogen and coagulation factors, II, V, VII, VIII, X, and XII. |
1(0,0,0,1) | Details |
| 6641583 | Lox CD: Effects of acute pesticide poisoning on blood clotting in the rat. Ecotoxicol Environ Saf. 1983 Oct;7(5):451-4. Male Sprague-Dawley rats were treated with 1 ml of diazinon or malathion, 1750 ppm given orally by gavage. Clotting determinations included the prothrombin time, partial thromboplastin time, fibrinogen, and coagulation factors II, V, VII, and X, plus the hematocrit and platelet count. |
1(0,0,0,1) | Details |
| 15281233 | Sweeney MI, Lyon ME: Selective effect of malathion on blood coagulation versus locomotor activity. J Environ Pathol Toxicol Oncol. 1999;18(3):203-11. |
0(0,0,0,0) | Details |
| 6662056 | Lox CD, Davis JR: The effects of long-term malathion or diazinon ingestion on the activity of hepatic synthesized clotting factors. Ecotoxicol Environ Saf. 1983 Dec;7(6):546-51. Clotting studies included the prothrombin time (PT), partial thromboplastin time (APTT), fibrinogen, and factors II, V, VII, X, plus the platelet count. |
1(0,0,0,1) | Details |