| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8347128 | Igisu H, Hamasaki N, Ikeda M: Highly cooperative inhibition of acetylcholinesterase by pentachlorophenol in human erythrocytes. Biochem Pharmacol. 1993 Jul 6;46(1):175-7. |
162(2,2,2,2) | Details |
| 9049051 | Matsumura H, Matsuoka M, Igisu H, Ikeda M: Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes. Arch Toxicol. 1997;71(3):151-6. Hexachlorophene (HCP), pentachlorophenol (PCP), 2,4,5-trichlorophenol (2,4,5-TCP) and 2,4,6-trichlorophenol (2,4,6-TCP) all hemolyzed washed human erythrocytes and inhibited acetylcholinesterase (AchE) activities in erythrocyte membrane. |
82(1,1,1,2) | Details |
| 7938978 | Igisu H, Matsumura H, Matsuoka M: [Acetylcholinesterase in the erythrocyte membrane] . J UOEH. 1994 Sep 1;16(3):253-62. |
2(0,0,0,2) | Details |
| 14599456 | Rios JC, Repetto G, Jos A, del Peso A, Salguero M, Camean A, Repetto M: Tribromophenol induces the differentiation of SH-SY5Y human neuroblastoma cells in vitro. Toxicol In Vitro. 2003 Oct-Dec;17(5-6):635-41. Tribromophenol is a pesticide with fungicide activity, presently used as a replacement of pentachlorophenol as a wood preservative, and as a flame retardant in electronic and electrotechnical devices. Acetylcholinesterase activity increased with the time of exposure in non-differentiated cells, while in differentiated cells the activity was doubled at 24 h. |
2(0,0,0,2) | Details |
| 6221918 | Hanke W, Gluth G, Bubel H, Muller R: Physiological changes in carps induced by pollution. Ecotoxicol Environ Saf. 1983 Apr;7(2):229-41. Several pollutants like DDT, atrazine, PCP, and others induce changes of and levels in serum, variations of the amount of liver and liver function, and exert changes of the activity of gill ATPase and acetylcholinesterase in brain and serum of carps. |
1(0,0,0,1) | Details |
| 15478171 | van der Schalie WH, Shedd TR, Widder MW, Brennan LM: Response characteristics of an aquatic biomonitor used for rapid toxicity detection. J Appl Toxicol. 2004 Sep-Oct;24(5):387-94. In the laboratory studies, the aquatic biomonitor responded to the majority of chemicals at the 96-h lc (50) within an hour or less, although substantially higher response times were found for malathion and pentachlorophenol. Although data are limited, the aquatic biomonitor appears to respond more rapidly to chemicals causing membrane irritation, narcosis or polar narcosis than to acetylcholinesterase inhibitors or oxidative phosphorylation uncouplers. |
1(0,0,0,1) | Details |
| 12825237 | Tang Y, Donnelly KC, Tiffany-Castiglioni E, Mumtaz MM: Neurotoxicity of polycyclic aromatic hydrocarbons and simple chemical mixtures. J Toxicol Environ Health A. 2003 May 23;66(10):919-40. In addition, PCP appeared to increase the inhibition of acetylcholinesterase by mipafox. |
1(0,0,0,1) | Details |
| 6871453 | Braginskaia FI, Sultanova GG, Zorina OM: [Effect of -containing pesticides on the hemolytic stability and acetylcholinesterase activity of erythrocytes]. Biull Eksp Biol Med. 1983 Jul;96(7):36-8. |
2(0,0,0,2) | Details |