| Name | CYP3A |
|---|---|
| Synonyms | CP33; CYP3; HLP; CYP3A; CP34; CYP 3A4; CYP 3; CYP3A3… |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8812189 | Dubois M, Plaisance H, Thome JP, Kremers P: Hierarchical cluster analysis of environmental pollutants through P450 induction in cultured hepatic cells. Ecotoxicol Environ Saf. 1996 Aug;34(3):205-15. The tested products fell into four major groups: a first group with pentachlorophenol, identified as a CYP3A inducer; a second group containing the methylcholanthrene-type inducers that increase CYP1A-related activities; a third class represented by dieldrin, a PB-type inducer; a fourth group including inert compounds or weak inducers. |
31(0,1,1,1) | Details |
| 12387828 | Barque JP, Abahamid A, Flinois JP, Beaune P, Bonaly J: Constitutive overexpression of immunoidentical forms of PCP-induced Euglena gracilis CYP-450. Biochem Biophys Res Commun. 2002 Oct 25;298(2):277-81. In this report, antibodies that are able to detect mammalian CYP proteins, namely the CYP1A1, CYP1A2, CYP2B1/B2, and CYP3A4 proteins, were used to investigate the expression of CYP-related proteins in Euglena gracilis (EG) cells under normal and PCP-treated conditions and in a EG-cell line adapted to PCP. |
2(0,0,0,2) | Details |
| 8759309 | Mehmood Z, Williamson MP, Kelly DE, Kelly SL: Metabolism of organochlorine pesticides: the role of human cytochrome P450 3A4. Chemosphere. 1996 Aug;33(4):759-69. In both in vitro and in vivo studies, hexachlorobenzene and pentachlorobenzene were metabolised into pentachlorophenol which was further transformed into tetrachlorohydroquinone. |
2(0,0,0,2) | Details |