Protein Information

Name carbonic anhydrase
Synonyms CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III…

Compound Information

Name thiabendazole
CAS

Reference List

PubMed Abstract RScore(About this table)
19186056 Crocetti L, Maresca A, Temperini C, Hall RA, Scozzafava A, Muhlschlegel FA, Supuran CT: A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1371-5. Epub 2009 Jan 19.

A sulfonamide derivative of the antihelmintic drug thiabendazole was prepared and investigated for inhibition of the zinc enzyme carbonic anhydrase CA (EC 4.2.1.1).
163(2,2,2,3) Details
530559 Fraunfelder FT: Interim report: National Registry of Possible Drug-Induced Ocular Side Effects. Ophthalmology. 1979 Jan;86(1):126-30.

Recent data concerning 1%, 2.4%, and 10% topical ocular phenylephrine, topical ocular local anesthetics, carbonic anhydrase inhibitors, diazepam, liquid high-protein diets, sodium fluoride gel, naproxen, and thiabendazole are reviewed.
31(0,1,1,1) Details
6397176 Fraunfelder FT, Meyer SM: Ocular toxicology update. Aust J Ophthalmol. 1984 Nov;12(4):391-4.

Over 75 cases of major haemopoietic events from carbonic anhydrase inhibitors are also reviewed.
Other drugs, such as adrenaline (epinephrine), ecothiopate (echothiophate), practolol, thiabendazole, and penicillamine are suspected of causing ocular pseudopemphigoid.
1(0,0,0,1) Details