| Name | CD8 |
|---|---|
| Synonyms | CD8; p32; MAL; CD8A; CD8a antigen; CD8a molecule; LEU2 T lymphocyte antigen; Leu2… |
| Name | diphenylamine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20356634 | Ni SJ, Qiu YH, Lu JH, Cao BB, Peng YP: Effect of cerebellar fastigial nuclear lesions on differentiation and function of thymocytes. J Neuroimmunol. 2010 Mar 29. On days 12 and 32 following the KA injection, percentages of thymocyte subpopulations including CD4 (-) CD8 (-), CD4 (+) CD8 (+), CD4 (+) CD8 (-) and CD4 (-) CD8 (+) cells, apoptotic DNA fragmentation of thymocytes, and levels of interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) in the serum were measured by flow cytometry, diphenylamine assay and enzyme-linked immunosorbent assay (ELISA), respectively. |
33(0,1,1,3) | Details |
| 10210284 | Zhang LH, Longley RE: Induction of apoptosis in mouse thymocytes by microcolin A and its synthetic analog. Life Sci. 1999;64(12):1013-28. Following incubation of the cells with Mic-1 (10-100 nM) or Mic-3 (10-100 nM), internucleosomal DNA fragmentation in apoptotic cells was detected by agarose gel electrophoresis and the diphenylamine (DPA) assay; the presence of hypodiploid nuclei assessed by propidium iodide (PI) staining; and the percentages of apoptotic and necrotic cells quantified by morphological observation and fluorescein labeled annexin-V binding. Furthermore, flow cytometric analysis using monoclonal antibodies specific to thymocyte subpopulations showed that the proportion of the early immature CD4+ CD8+ T-cell subpopulation in thymocytes was selectively decreased by both agents with a corresponding increase of other subpopulations, indicating that CD4+ CD8+ T cells are the most likely targets of Mic-1 and Mic-3. |
1(0,0,0,1) | Details |
| 7805721 | Wang H, Gill RF, Lichlyter D, Iglesias A, Bluethmann H, Wei WZ: Deletion of CD4+ T cells and thymocytes by apoptosis in mouse mammary tumor virus (C4)-infected V beta 2 transgenic mice. Eur J Immunol. 1994 Dec;24(12):2950-6. In older mice injected with MMTV (C4), splenic CD8+ T cells were significantly elevated. To determine if T cells or thymocytes were deleted through apoptosis, DNA fragmentation was examined by flow cytometry and diphenylamine (DPA) binding assay. |
1(0,0,0,1) | Details |