Protein Information

Name L selectin
Synonyms CD62 antigen ligand; CD62L; CD62L antigen; HLHRC; L selectin; L selectin precursor; LAM 1; LAM1…

Compound Information

Name diphenylamine
CAS

Reference List

PubMed Abstract RScore(About this table)
12147693 Gomez-Gaviro MV, Gonzalez-Alvaro I, Dominguez-Jimenez C, Peschon J, Black RA, Sanchez-Madrid F, Diaz-Gonzalez F: Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs. J Biol Chem. 2002 Oct 11;277(41):38212-21. Epub 2002 Jul 29.

The presence of a carboxylic acid group in the diphenylamine (N-phenylanthranilic acid) highly increased its ability to reduce the L-selectin surface expression in neutrophils.
207(2,3,5,7) Details