Protein Information

Name ADH1
Synonyms ADH 1; ADH1; ADH1A; Alcohol dehydrogenase 1; Alcohol dehydrogenase 1A; Alcohol dehydrogenase alpha subunit; Alcohol dehydrogenase 1s; Alcohol dehydrogenase 1As…

Compound Information

Name allyl alcohol
CAS 2-propen-1-ol

Reference List

PubMed Abstract RScore(About this table)
640376 Thirion JP, Talbot B: Alcohol dehydrogenase mutants of Chinese hamster somatic cells resistant to allyl alcohol. Genetics. 1978 Feb;88(2):343-56.

Several mutants, Adh-1, Adh-2, Adh-9 and Adh-13, resistant to allyl alcohol were characterized.
6(0,0,1,1) Details
2034210 Wisman E, Koornneef M, Chase T, Lifshytz E, Ramanna MS, Zabel P: Genetic and molecular characterization of an Adh-1 null mutant in tomato. Mol Gen Genet. 1991 Apr;226(1-2):120-8.

Treatment of tomato seeds with ethyl methanesulphonate (EMS) followed by allyl alcohol selection of M2 seeds has led to the identification of one plant (B15-1) heterozygous for an alcohol dehydrogenase (Adh) null mutation.
5(0,0,0,5) Details
8625422 Grey M, Schmidt M, Brendel M: Overexpression of ADH1 confers hyper-resistance to formaldehyde in Saccharomyces cerevisiae. Curr Genet. 1996 Apr;29(5):437-40.

3(0,0,0,3) Details
3377754 Jacobs M, Dolferus R, Van den Bossche D: Isolation and biochemical analysis of ethyl methanesulfonate-induced alcohol dehydrogenase null mutants of arabidopsis thaliana (L.) Heynh. Biochem Genet. 1988 Feb;26(1-2):105-22.

Several mutants have been isolated at the Arabidopsis thaliana (L.) Heynh. alcohol dehydrogenase (ADH) gene locus using allyl alcohol selection on ethyl methanesulfonate (EMS)-mutagenized seeds.
Eleven mutants were isolated in the ADH1-A electrophoretic allele, and 21 in the ADH1-S allele.
3(0,0,0,3) Details
16073427 Freeling M: Spontaneous forward mutation versus reversion frequencies for maize Adh1 in pollen. Nature. 1977 May 12;267(5607):154-6.

And second, ADH1- pollen grains survive allyl alcohol (C=C-C-OH) vapour concentrations which kill ADH1+ grains; this selection scheme was developed for yeast by Megnet.
7(0,0,1,2) Details
3549443 Hall JG, Wills C: Functional alcohol dehydrogenase mutants of Saccharomyces cerevisiae conferring temperature-conditional allyl alcohol resistance. Genetics. 1987 Jan;115(1):65-71.

Selection for allyl alcohol resistance in respiratory incompetent yeast is a highly specific method for isolating functional mutations at ADH1, the gene coding for the cytoplasmic alcohol dehydrogenase, ADHI.
6(0,0,1,1) Details
3319769 Hall JG, Wills C: Conditional overdominance at an alcohol dehydrogenase locus in yeast. Genetics. 1987 Nov;117(3):421-7.

Here we report an example of overdominance that is temperature- and allyl alcohol-dependent and due to heterozygosity at the ADH1 locus, involving two ADHI functional mutants.
6(0,0,1,1) Details