Protein Information

Name cyclooxygenase 2
Synonyms COX 2; COX2; PHS2; PGG/HS; Cyclooxygenase 2; Cyclooxygenase 2b; Cycloxygenase 2; PGH synthase 2…

Compound Information

Name methabenzthiazuron
CAS

Reference List

PubMed Abstract RScore(About this table)
15250241 Wu GS, Zou SQ, Wu XY, Qiu FZ: Effects of cyclooxygenase-2 antisense vector on proliferation of human cholangiocarcinoma cells. Chin Med Sci J. 2004 Jun;19(2):89-92.

The proliferative status of transfected cells was measured by using methabenzthiazuron (MTT) assay; Cell cycle and apoptosis were analyzed by using flow cytometry.
2(0,0,0,2) Details
12800245 Wu GS, Zou SQ, Liu ZR, Tang ZH, Wang JH: Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E2 pathway in human cholangiocarcinoma cell lines. World J Gastroenterol. 2003 Jun;9(6):1302-6.

METHODS: Cyclooxygenase-2-overexpressing human cholangiocarcinoma cell line QBC939 and cyclooxygenase-2-deficient human cholangiocarcinoma cell line SK-CHA-1 were used in the present study.
The anti-proliferative effect was measured by methabenzthiazuron (MTT) assay; apoptosis was determined by transferase-mediated dUTP nick end labeling (TUNEL) detection and transmission electron microscopy (TEM).
2(0,0,0,2) Details
15934305 Wu G, Yi J, Di F, Zou S, Li X: Celecoxib inhibits proliferation and induces apoptosis via cyclooxygenase-2 pathway in human pancreatic carcinoma cells. J Huazhong Univ Sci Technolog Med Sci. 2005;25(1):42-4.

In order to evaluate the effects and mechanisms of celecoxib in inhibiting proliferation and inducing apoptosis on human pancreatic carcinoma cells, the anti-proliferative effect was measured by using methabenzthiazuron (MTT) assay.
2(0,0,0,2) Details
12717864 Wu GS, Zou SQ, Liu ZR, Wang DY: Bile from a patient with anomalous pancreaticobiliary ductal union promotes the proliferation of human cholangiocarcinoma cells via COX-2 pathway. World J Gastroenterol. 2003 May;9(5):1094-7.

The proliferative effect of bile was measured by methabenzthiazuron (MTT) assay; COX-2 mRNA was examined by semi-quantitative reverse transcription polymerase chain reaction (RT-PCR).
The proliferative activity of APBDU bile can be abolished by addition of cyclooxygenase-2 specific inhibitor celecoxib.
1(0,0,0,1) Details
12508379 Wu GS, Zou SQ, Luo XW, Wu JH, Liu ZR: Proliferative activity of bile from congenital choledochal cyst patients. World J Gastroenterol. 2003 Jan;9(1):184-7.


The proliferative effect of bile was measured by using Methabenzthiazuron (MTT) assay; Cell cycle and apoptosis were analyzed by using flow cytometry (FCM), and the PGE (2) levels in the supernatant of cultured cholangiocarcinoma cells were quantitated by enzyme-linked immunoabsorbent assay (ELISA).
0(0,0,0,0) Details