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Luo J, Cao ZH, Liu MF, Zuo S, Dong JQ, Zou SQ: [Effect of adenovirus-mediated mutant exogenous P27kip1 gene expression on the chemosensitivities of cholangiocarcinoma cell line]. Zhonghua Wai Ke Za Zhi. 2006 Oct 1;44(19):1349-52.
OBJECTIVE: To investigate the effects of mutant exogenous P27 (kip1) gene on chemosensitivity of human cholangiocarcinoma cell line. The effects of 5-fluorouracil (5-FU), mitomycin C (MMC) and cyclophosphamide (CTX) on the transfected cells were detected by assaying the apoptotic rate and growth inhibition by methabenzthiazuron (MTT) assay and flow cytometry (FCM). |
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