| Name | Fas Ligand |
|---|---|
| Synonyms | APT1LG1; FAS; APTL; Apoptosis (APO 1) antigen ligand 1; Apoptosis antigen ligand; Apoptosis antigen ligand 1; CD178; CD178 antigen… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16487513 | Ivanov VN, Hei TK: Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells. Exp Cell Res. 2006 May 1;312(8):1401-17. Epub 2006 Feb 17. |
32(0,1,1,2) | Details |
| 14962100 | Liao WT, Chang KL, Yu CL, Chen GS, Chang LW, Yu HS: Arsenic induces human keratinocyte apoptosis by the FAS/FAS ligand pathway, which correlates with alterations in nuclear factor-kappa B and activator protein-1 activity. J Invest Dermatol. 2004 Jan;122(1):125-9. To investigate the mechanism of arsenic-induced apoptosis and related alterations in NF-kappa B and AP-1 activity, we exposed cultured human foreskin keratinocytes to different concentrations of sodium arsenite. At higher concentrations (> or =5 microM), arsenic induced keratinocyte apoptosis by the Fas/Fas ligand (FasL) pathway. |
1(0,0,0,1) | Details |
| 17545621 | Ivanov VN, Zhou H, Hei TK: Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells. Cancer Res. 2007 Jun 1;67(11):5397-407. We show in the present study that gamma-irradiation, as well as alpha-particle exposure, dramatically increases the susceptibility of melanoma cells to recombinant tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis via up-regulation of surface TRAIL-receptor 1/receptor 2 (DR4/DR5) levels and to Fas ligand-mediated apoptosis via up-regulation of surface Fas levels. |
1(0,0,0,1) | Details |