Protein Information

Name 3 beta hydroxysteroid dehydrogenase
Synonyms 3 beta hydroxysteroid dehydrogenase; 3 beta hydroxysteroid dehydrogenase homolog protein; 3 beta hydroxysteroid dehydrogenase pseudogene; 3 beta hydroxysteroid dehydrogenase pseudogenes

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
12883085 Chattopadhyay S, Pal Ghosh S, Ghosh D, Debnath J: Effect of dietary co-administration of sodium selenite on sodium arsenite-induced ovarian and uterine disorders in mature albino rats. Toxicol Sci. 2003 Oct;75(2):412-22. Epub 2003 Jul 25.

The subchronic treatment of mature female Wistar-strain albino rats in diestrous phase with sodium arsenite at a dose of 0.4 ppm/100 g body weight/rat/day via drinking water for period of 28 days (seven estrous cycles) caused a significant reduction in the plasma levels of leutinizing hormone (LH), follicle-stimulating hormone (FSH), and estradiol along with a significant decrease in ovarian activities of delta five, 3 beta-hydroxysteroid dehydrogenase (Delta5,3beta-HSD), and 17 beta-hydroxysteroid dehydrogenase (17beta-HSD) followed by a reduction in ovarian and uterine peroxidase activities.
31(0,1,1,1) Details
10656165 Chattopadhyay S, Ghosh S, Chaki S, Debnath J, Ghosh D: Effect of sodium arsenite on plasma levels of gonadotrophins and ovarian steroidogenesis in mature albino rats: duration-dependent response. J Toxicol Sci. 1999 Dec;24(5):425-31.

Weights of ovary, uterus and vagina along with biochemical activities of ovarian delta 5-3 beta-hydroxysteroid dehydrogenase (delta 5-3 beta-HSD) and 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) and plasma levels of LH, FSH and estrogen were measured in mature rats of the Wistar strain at diestrous phase following subchronic treatment with sodium arsenite at a dose of 0.4 ppm/rat/day for 16 days (4 estrous cycles) and 28 days (7 estrous cycles).
6(0,0,1,1) Details