| Name | JAK2 |
|---|---|
| Synonyms | JAK 2; JAK2; JAK2 protein; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); Tyrosine protein kinase 2; Tyrosine protein kinase JAK2; JAK2 proteins… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17689208 | Huang YC, Hung WC, Kang WY, Chen WT, Chai CY: Expression of STAT3 and Bcl-6 oncoprotein in sodium arsenite-treated SV-40 immortalized human uroepithelial cells. Toxicol Lett. 2007 Aug 30;173(1):57-65. Epub 2007 Jun 20. Sodium arsenite treatment reduced Jak-2 protein expression in a dose-dependent manner. |
82(1,1,1,2) | Details |
| 17070520 | Ivanov VN, Hei TK: Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression. Exp Cell Res. 2006 Dec 10;312(20):4120-38. Epub 2006 Sep 28. Sodium arsenite is known to suppress both the IKK-NF-kappaB and JAK2-STAT3 signaling pathways and to activate the MAPK/JNK-cJun pathways, thereby committing some cancers to undergo apoptosis. |
81(1,1,1,1) | Details |