Protein Information

Name TRbeta
Synonyms SELZ; TR3; TR; TRB; SelZ; Selenoprotein Z; TR BETA; TRXR 2…

Compound Information

Name acetochlor
CAS

Reference List

PubMed Abstract RScore(About this table)
11764152 Veldhoen N, Helbing CC: Detection of environmental endocrine-disruptor effects on gene expression in live Rana catesbeiana tadpoles using a tail fin biopsy technique. Environ Toxicol Chem. 2001 Dec;20(12):2704-8.

Tail fin biopsy and reverse transcription-polymerase chain reaction analyses of the thyroid hormone (TH)-responsive gene, TH receptor beta (TRbeta), demonstrate for the first time that a known accelerant of TH-induced metamorphosis, acetochlor, can significantly enhance TH-induced TRbeta mRNA levels within 24 h at an environmentally relevant dose.
31(0,1,1,1) Details
16949162 Helbing CC, Ovaska K, Ji L: Evaluation of the effect of acetochlor on thyroid hormone receptor gene expression in the brain and behavior of Rana catesbeiana tadpoles. Aquat Toxicol. 2006 Oct 25;80(1):42-51. Epub 2006 Sep 1.

Premetamorphic tadpoles exposed to 10 nM acetochlor with and without 100 nM T (3) for 4 days showed substantial increases in TRalpha and TRbeta transcript levels and significant decreases in the TRalpha/TRbeta ratios in their brains.
6(0,0,1,1) Details