Protein Information

Name UGT1A1
Synonyms Bilirubin specific UDPGT isozyme 1; UGT 1; UGT1; GNT1; HUG BR1; Phenol/billirubinUDP glucuronosyltransferase 1; UDP glycosyltransferase 1 family polypeptide A1; UDP glucuronosyl transferase 1A1…

Compound Information

Name sulfuric acid
CAS sulfuric acid

Reference List

PubMed Abstract RScore(About this table)
11950788 Walle UK, Walle T: Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements. Drug Metab Dispos. 2002 May;30(5):564-9.

4(0,0,0,4) Details
16715376 Nikolic D, Li Y, Chadwick LR, van Breemen RB: In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.). Pharm Res. 2006 May;23(5):864-72. Epub 2006 May 16.


Incubations with various cDNA-expressed UDP-glucuronosyltransferases indicated that the isozymes UGT1A1, UGT1A6, UGT1A8, and UGT1A9 were responsible for glucuronidation of 8-PN.
1(0,0,0,1) Details
11950790 Otake Y, Hsieh F, Walle T: Glucuronidation versus oxidation of the flavonoid galangin by human liver microsomes and hepatocytes. Drug Metab Dispos. 2002 May;30(5):576-81.


This highly efficient glucuronidation appeared to be catalyzed mainly by the UDP-glucuronosyltransferase (UGT) 1A9 isoform but also by UGT1A1 and UGT2B15.
1(0,0,0,1) Details