| Name | sorbitol dehydrogenase |
|---|---|
| Synonyms | L iditol 2 dehydrogenase; SORD; SORD 1; SORD 2; SORD1; SORD2; Sorbitol dehydrogenase; Sorbitol dehydrogenase 1… |
| Name | cyanamide |
|---|---|
| CAS | cyanamide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10596409 | Bossaert K, Lonneux JF, Godeau JM, Peeters J, Losson B: Serological and biochemical follow-up in cattle naturally infected with Fasciola hepatica, and comparison with a climate model for predicting risks of fasciolosis. Vet Res. 1999 Nov-Dec;30(6):615-28. Each pasture was divided into two plots: one was treated with cyanamide and the other was left untreated. Body weight gains, anti-Fasciola antibody levels, faecal egg counts, levels of sorbitol dehydrogenase (SDH) and gamma-glutamyl transferase (gamma GT), packed cell volumes, white blood cells and differential leucocyte counts were determined monthly. |
1(0,0,0,1) | Details |
| 3508430 | Younes M, Strubelt O: -induced hepatotoxicity: a role for free radicals. Free Radic Res Commun. 1987;3(1-5):19-26. Perfusion of isolated rat livers with at a concentration of 2 g/l (%o) resulted in a release of glutamate-pyruvate-transaminase (GPT) and sorbitol dehydrogenase (SDH) into the perfusate as markers of toxicity. Inhibition of alcohol dehydrogenase by 4-methylpyrazole or of aldehyde dehydrogenase by cyanamide totally abolished hepatotoxicity despite of a severalfold increase in concentration in the perfusate. |
1(0,0,0,1) | Details |
| 2886311 | Rikans LE: The oxidation of acrolein by rat liver aldehyde dehydrogenases. Drug Metab Dispos. 1987 May-Jun;15(3):356-62. The metabolism of acrolein by low Km aldehyde dehydrogenase activities was markedly depressed in mitochondrial or cytosolic fractions from rats pretreated with cyanamide (2 mg/kg for 1 hr) or disulfiram (100 mg/kg for 24 hr). Hepatotoxicity was assessed on the basis of elevated serum alanine aminotransferase and sorbitol dehydrogenase activities and the loss of microsomal cytochrome P-450. |
1(0,0,0,1) | Details |