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Wellsow J, Kovar KA, Machulla HJ: Molecular modeling of potential new and selective PET radiotracers for the serotonin transporter. J Pharm Pharm Sci. 2002 Sep-Dec;5(3):245-57.
Another innovative suggestion is the replacement of the sulfur bridge with a cyanamide group and a fluoroethylamino group.
The main purpose of this study was to design potential new and selective PET radiotracers for the SERT and to predict their binding affinity at both the SERT and the norepinephrine transporter. |
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