Name | beta actin |
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Synonyms | ACTB; Actin beta; Beta actin; Beta cytoskeletal actin; PS1TP5BP1; Actin betas; Beta actins; Beta cytoskeletal actins |
Name | acrolein |
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CAS | 2-propenal |
PubMed | Abstract | RScore(About this table) | |
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19271284 | Chung WG, Miranda CL, Stevens JF, Maier CS: Hop proanthocyanidins induce apoptosis, protein carbonylation, and cytoskeleton disorganization in human colorectal adenocarcinoma cells via reactive species. Food Chem Toxicol. 2009 Apr;47(4):827-36. Mass spectrometry-based proteomic analysis in combination with 2-alkenal-specific immunochemical detection identified beta-actin and protein disulfide isomerase as major putative targets of acrolein adduction. |
31(0,1,1,1) | Details |
19709606 | Chung WG, Miranda CL, Stevens JF, Maier CS: Hop proanthocyanidins induce apoptosis, protein carbonylation, and cytoskeleton disorganization in human colorectal adenocarcinoma cells via reactive species. Food Chem Toxicol. 2009 Jan 15. Mass spectrometry-based proteomic analysis in combination with 2-alkenal-specific immunochemical detection identified beta-actin and protein disulfide isomerase as major putative targets of acrolein adduction. |
31(0,1,1,1) | Details |
17570602 | Mello CF, Sultana R, Piroddi M, Cai J, Pierce WM, Klein JB, Butterfield DA: Acrolein induces selective protein carbonylation in synaptosomes. Neuroscience. 2007 Jul 13;147(3):674-9. Epub 2007 Jun 14. Proteomic analysis (two-dimensional electrophoresis followed by mass spectrometry) revealed that tropomyosin-3-gamma isoform 2, tropomyosin-5, beta-actin, mitochondrial Tu translation elongation factor (EF-Tu (mt)) and voltage-dependent anion channel (VDAC) were significantly carbonylated by acrolein. |
6(0,0,1,1) | Details |
12392766 | Butterfield DA, Castegna A, Lauderback CM, Drake J: Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging. 2002 Sep-Oct;23(5):655-64. Two reactive products of lipid peroxidation are the alkenals, (HNE) and 2-propenal (acrolein). kinase (CK) and beta-actin have increased carbonyl groups, and Glt-1, transporter, has increased binding of HNE in AD. |
1(0,0,0,1) | Details |