Protein Information

Name Toll like receptor 4
Synonyms CD284; CD284 antigen; TLR 4; TLR4; TOLL; Toll like receptor 4; Toll like receptor 4 precursor; hToll…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
18414004 Lee JS, Lee JY, Lee MY, Hwang DH, Youn HS: Acrolein with an alpha, beta-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4. Mol Cells. 2008 Apr 30;25(2):253-7. Epub 2008 Mar 31.
165(2,2,2,5) Details
17920563 Youn HS, Lee JK, Choi YJ, Saitoh SI, Miyake K, Hwang DH, Lee JY: Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization. Biochem Pharmacol. 2008 Jan 15;75(2):494-502. Epub 2007 Sep 2.

4(0,0,0,4) Details
18306459 Zhao BS, Huo HR, Ma YY, Liu HB, Li LF, Sui F, Li CH, Guo SY, Jiang TL: Effects of 3-phenyl-propenal on the expression of toll-like receptors and downstream signaling components on raw264.7 murine macrophages. Am J Chin Med. 2008;36(1):159-69.


The aim of the present study was to investigate the effects of 3-phenyl-propenal on the expression of toll-like receptor 3 (TLR3), TLR4 and the downstream signaling components on Raw264.7 murine microphages.
4(0,0,0,4) Details