Protein Information

Name immunoglobulin (protein family or complex)
Synonyms Immunoglobulin; Immunoglobulins

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
10806334 Sugahara T, Murakami F, Yamada Y, Sasaki T: The mode of actions of lysozyme as an immunoglobulin production stimulating factor. Biochim Biophys Acta. 2000 Jun 1;1475(1):27-34.

However, the enzyme was ineffective to accelerate IgM production by translation-suppressed HB4C5 cells treated with cycloheximide or sodium fluoride.
6(0,0,0,6) Details
19002935 Takenouchi S, Sugahara T: Lactate dehydrogenase enhances immunoglobulin production by human hybridoma and human peripheral blood lymphocytes. Cytotechnology. 2003 Sep;42(3):133-43.

The immunoglobulin production-stimulating factors (IPSFs) effect of LDH was slightly weakened by sodium fluoride (translation inhibitor) treatment of HB4C5.
4(0,0,0,4) Details
18997433 Nishimoto S, Goto Y, Morishige H, Shiraishi R, Doi M, Akiyama K, Yamauchi S, Sugahara T: Mode of action of the immunostimulatory effect of collagen from jellyfish. Biosci Biotechnol Biochem. 2008 Nov;72(11):2806-14. Epub 2008 Nov 7.

We have previously demonstrated that collagen from jellyfish simulated immunoglobulin and cytokine production by human-human hybridoma line HB4C5 cells and by human peripheral blood lymphocytes (hPBL).
This collagen also enhanced IgM production by translation-suppressed HB4C5 cells that had been treated with sodium fluoride, but was ineffective in accelerating IgM production by HB4C5 cells treated with cycloheximide.
2(0,0,0,2) Details
15203033 Schlatterer B, Baeker R, Schlatterer K: Improved purification of beta-lactoglobulin from acid whey by means of ceramic hydroxyapatite chromatography with sodium fluoride as a displacer. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Aug 5;807(2):223-8.

Co-eluted contaminants are traces of immunoglobulin G, serum albumin and lactoferrin.
1(0,0,0,1) Details
11513842 Peh KH, Moulson A, Wan BY, Assem EK, Pearce FL: Role of nitric oxide in histamine release from human basophils and rat peritoneal mast cells. Eur J Pharmacol. 2001 Aug 17;425(3):229-38.


None of the inhibitors of NO production had any striking effect on histamine release induced by anti-rat immunoglobulin E (IgE), compound 48/80, sodium fluoride, phospholipase C, 1,2-dioctanoyl-sn-glycerol or ionophore A23187.
0(0,0,0,0) Details