| Name | G protein coupled receptor |
|---|---|
| Synonyms | ASRT 2; ASRT2; G protein coupled receptor 154; G protein coupled receptor for asthma susceptibility; G protein coupled receptor; G protein coupled receptor PGR14; GPR154; GPRA… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8645978 | Koller M, Hilger RA, Rihoux JP, Konig W: exerts anti-inflammatory effects on human neutrophils. . Int Arch Allergy Immunol. 1996 May;110(1):52-6. The inflammatory mediators were analyzed after cellular activation with different stimuli: the Ca ionophore A23187, which bypasses membranous signal transduction elements; the bacterial peptide formyl--leucyl- (fMLP), which activates cells by binding to a GTP-protein (G-protein)-coupled receptor, and with sodium fluoride (NaF), which directly activates G-proteins. |
31(0,1,1,1) | Details |
| 15477420 | Waleh N, Kajino H, Marrache AM, Ginzinger D, Roman C, Seidner SR, Moss TJ, Fouron JC, Vazquez-Tello A, Chemtob S, Clyman RI: --mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control. Circulation. 2004 Oct 19;110(16):2326-32. Epub 2004 Oct 11. |
2(0,0,0,2) | Details |
| 9169417 | Abell AN, Segaloff DL: Evidence for the direct involvement of transmembrane region 6 of the lutropin/choriogonadotropin receptor in activating Gs. J Biol Chem. 1997 Jun 6;272(23):14586-91. Significantly, these data are the first to demonstrate the ability of a transmembrane portion of a G protein-coupled receptor, in the absence of any contributions from an intracellular loop region, to activate a G protein. |
1(0,0,0,1) | Details |
| 18805511 | Assem el-SK, Peh KH, Wan BY, Middleton BJ, Dines J, Marson CM: Effects of a selection of histone deacetylase inhibitors on mast cell activation and airway and colonic smooth muscle contraction. Int Immunopharmacol. 2008 Dec 20;8(13-14):1793-801. Epub 2008 Sep 19. Pre-incubation (up to 6 h) with 10-40 microM of SAHA, diamide (1), or MGCD0103 caused significant inhibition of the antigen-induced contraction of sensitised guinea pig tracheal rings as well as inhibition of the contraction induced by and carbachol (G-protein coupled receptor agonists), while (1 mM) and (100 microM) were weak inhibitors. Contraction of tracheal rings by sodium fluoride (NaF, a non-selective G-protein activator), KCl and a peroxyl radical generator was blocked by MGCD0103. |
1(0,0,0,1) | Details |
| 9316442 | Mitchell J, Bansal A: Dexamethasone increases G alpha q-11 expression and hormone-stimulated phospholipase C activity in UMR-106-01 cells. Am J Physiol. 1997 Sep;273(3 Pt 1):E528-35. Glucocorticoids regulate responsiveness of many cells to hormones that bind to G protein-coupled receptors. |
1(0,0,0,1) | Details |