Protein Information

Name PP1
Synonyms NPY4 R; PP1; NPY4R; Neuropeptide Y receptor type 4; PPYR 1; PPYR1; Pancreatic polypeptide receptor 1; Y4…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
11494123 Jaumot M, Hancock JF: Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions. Oncogene. 2001 Jul 5;20(30):3949-58.

General serine-threonine phosphatase inhibitors such sodium fluoride, or ss-glycerophosphate and sodium pyrophosphate, or specific PP1 and PP2A inhibitors including microcystin-LR, protein phosphatase 2A inhibitor I (1) or protein phosphatase inhibitor 2 all abrogate H-Ras and K-Ras dependent Raf-1 activation in vitro.
34(0,1,1,4) Details
9648724 Sayeski PP, Ali MS, Harp JB, Marrero MB, Bernstein KE: Phosphorylation of p130Cas by angiotensin II is dependent on c-Src, intracellular Ca2+, and protein kinase C. Circ Res. 1998 Jun 29;82(12):1279-88.


The Ang II-induced tyrosine phosphorylation of p130Cas was also dependent on an active Src family tyrosine kinase, since it could be blocked by the Src kinase inhibitors geldanamycin and PP1.
1(0,0,0,1) Details