Protein Information

Name glutathione transferase
Synonyms GST class mu 2; GST 4; GST4; GSTM; GSTM 2; GSTM2; GSTM2 2; GSTmu3…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
9490002 Dierickx PJ: Activation by sodium fluoride of drug-metabolizing enzymes in rat hepatoma-derived Fa32 cells. FEBS Lett. 1998 Jan 30;422(2):185-8.

Sodium fluoride activated the phase I ethoxyresorufin-O-deethylase (to 240%) and pentoxyresorufin-O-depentylase (to 156%), and the phase II glutathione transferase to 120% of the basal activities in rat hepatoma-derived Fa32 cells.
81(1,1,1,1) Details
20306234 Blaszczyk I, Birkner E, Kasperczyk S: Influence of Methionine on Toxicity of Fluoride in the Liver of Rats. Biol Trace Elem Res. 2010 Mar 20.

The aim of the studies conducted has been to determine what influence the administration of methionine during intoxication with sodium fluoride may have upon the selected enzymes of the antioxidative system in rat liver.
The influence of administered NaF and Met was examined by analyzing the activity of the antioxidative enzymes: superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glutathione transferase in the liver.
1(0,0,0,1) Details