Protein Information

Name sorbitol dehydrogenase
Synonyms L iditol 2 dehydrogenase; SORD; SORD 1; SORD 2; SORD1; SORD2; Sorbitol dehydrogenase; Sorbitol dehydrogenase 1…

Compound Information

Name acrylonitrile
CAS 2-propenenitrile

Reference List

PubMed Abstract RScore(About this table)
2592735 Ivanov V, Rahier J, Lauwerys R: Lipid peroxidation in acrylonitrile-treated rats, evidenced by elevated ethane production. J Appl Toxicol. 1989 Oct;9(5):353-8.

The intraperitoneal administration of acrylonitrile (greater than 25 mg kg-1) to rats is associated with an increased production of ethane and a rise of the serum activity of the cytosolic enzyme, sorbitol dehydrogenase.
81(1,1,1,1) Details
3388448 Tandon R, Saxena DK, Chandra SV, Seth PK, Srivastava SP: Testicular effects of acrylonitrile in mice. Toxicol Lett. 1988 Jul;42(1):55-63.

Daily oral administration of acrylonitrile (10 mg/kg body weight) to mice for a period of 60 days caused a significant decrease in the activity of testicular sorbitol dehydrogenase and acid phosphatase, and an increase in that of lactate dehydrogenase and beta-glucuronidase.
6(0,0,1,1) Details