| Name | glutathione S transferase T1 |
|---|---|
| Synonyms | GST class theta; GST class theta 1; GSTT 1; GSTT1; GSTT1 protein; Glutathione S transferase theta 1; Glutathione transferase T1 1; glutathione S transferase T1… |
| Name | ethylene dibromide |
|---|---|
| CAS | 1,2-dibromoethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8565128 | Thier R, Pemble SE, Kramer H, Taylor JB, Guengerich FP, Ketterer B: Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium. Carcinogenesis. 1996 Jan;17(1):163-6. In Salmonella typhimurium TA1535 expressing the rat GST5-5 the number of revertants was increased compared to the control strain by CH2Br2, ethylene dibromide (EDB) and 1,2,3,4-diepoxybutane (BDE); in contrast, mutagenicity of 1,2-epoxy-3-(4'-nitro-phenoxy) propane (EPNP) was reduced. |
5(0,0,0,5) | Details |
| 19664997 | Josephy PD, Kent M, Mannervik B: Single-nucleotide polymorphic variants of human glutathione transferase T1-1 differ in stability and functional properties. Arch Biochem Biophys. 2009 Oct 1;490(1):24-9. Epub 2009 Aug 6. Ethylene dibromide (EDB), which is activated by GST T1-1, produces a potent response in the mutation assay. |
3(0,0,0,3) | Details |
| 12902151 | Ross MK, Pegram RA: [35S]-labeling of the Salmonella typhimurium pool to assess -mediated DNA binding by 1,2-dibromoethane. Chem Biol Interact. 2003 Jul 25;146(1):39-49. The strain of Salmonella used in this study had been transformed previously with the gene that codes for rat glutathione transferase theta 1-1 (GSTT1-1), an enzyme that can catalyze formation of genotoxic GSH conjugates. |
2(0,0,0,2) | Details |