Protein Information

Name carbonic anhydrase
Synonyms CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III…

Compound Information

Name naphthalene
CAS naphthalene

Reference List

PubMed Abstract RScore(About this table)
17222003 Sun J, Kitova EN, Klassen JS: Method for stabilizing protein-ligand complexes in nanoelectrospray ionization mass spectrometry. Anal Chem. 2007 Jan 15;79(2):416-25.

The stabilizing effect of imidazole in nanoES-MS is further demonstrated for the interaction between carbonic anhydrase II and 5-(dimethylamino) naphthalene-1-sulfonamide.
81(1,1,1,1) Details
18404434 Coppi E, Pugliese AM, Stephan H, Muller CE, Pedata F: Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices. Purinergic Signal. 2007 Jun;3(3):203-19. Epub 2007 Jan 3.

ATPgammaS-mediated inhibition was reduced by the P2 antagonist suramin [8-(3-benzamido-4-methylbenzamido) naphthalene-1,3,5-trisulfonate] at the somatic level and by other P2 blockers, PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonate) and MRS 2179 (2'-deoxy-N (6)-methyladenosine 3',5'-bisphosphate), at the dendritic level.
3(0,0,0,3) Details
19684252 Costa BM, Feng B, Tsintsadze TS, Morley RM, Irvine MW, Tsintsadze V, Lozovaya NA, Jane DE, Monaghan DT: N-methyl-D-aspartate (NMDA) receptor NR2 subunit selectivity of a series of novel piperazine-2,3-dicarboxylate derivatives: preferential blockade of extrasynaptic NMDA receptors in the rat hippocampal CA3-CA1 synapse. J Pharmacol Exp Ther. 2009 Nov;331(2):618-26. Epub 2009 Aug 14.

Replacement of the phenanthrene moiety of PPDA with naphthalene or anthracene did not improve selectivity.
2(0,0,0,2) Details
18331041 Kim HM, Jeong BH, Hyon JY, An MJ, Seo MS, Hong JH, Lee KJ, Kim CH, Joo T, Hong SC, Cho BR: Two-photon fluorescent turn-on probe for lipid rafts in live cell and tissue. J Am Chem Soc. 2008 Apr 2;130(13):4246-7. Epub 2008 Mar 11.

We report a new two-photon fluorescence turn-on probe 6-[(E)-3-oxo-1-dodecenyl]-2-[N-methyl-N-(carboxymethyl) amino] naphthalene (CL2) that is designed specifically for visualizing lipid rafts in living cells and tissues.
This probe emits much brighter two-photon excited fluorescence in lipid rafts than in non-raft domains and allows direct visualization of the lipid rafts in the live cells and pyramidal neuron layer of the CA1 region at a depth of 100-250 mum in live tissues using two-photon microscopy.
1(0,0,0,1) Details
17002885 Salemi Z, Hosseinkhani S, Ranjbar B, Nemat-Gorgani M: Interaction of native and apo-carbonic anhydrase with hydrophobic adsorbents: A comparative structure-function study. J Biochem Mol Biol. 2006 Sep 30;39(5):636-41.

In the present study, an apo form of the enzyme was prepared by removal of zinc and a comparative study was performed on some characteristic features of the apo and native forms by far- and near-UV circular dichroism (CD), intrinsic fluorescent spectroscopy, 1-anilino naphthalene-8-sulfonate (ANS) binding, fluorescence quenching by acrylamide, and Tm measurement.
1(0,0,0,1) Details