Protein Information

Name transthyretin
Synonyms ATTR; HsT2651; PALB; Prealbumin; TBPA; TTR; Transthyretin; Transthyretin precursor…

Compound Information

Name naphthalene
CAS naphthalene

Reference List

PubMed Abstract RScore(About this table)
17630783 Wilkinson-White LE, Easterbrook-Smith SB: Characterization of the binding of Cu (II) and Zn (II) to transthyretin: effects on amyloid formation. Biochemistry. 2007 Aug 7;46(31):9123-32. Epub 2007 Jul 14.

Cu (II) gave dose-dependent quenching of the tryptophan fluorescence of transthyretin and the fluorescence of 1-anilino-8-naphthalene sulfonate bound to it.
34(0,1,1,4) Details
19954984 Lima LM, Silva Vde A, Palmieri Lde C, Oliveira MC, Foguel D, Polikarpov I: Identification of a novel ligand binding motif in the transthyretin channel. Bioorg Med Chem. 2010 Jan 1;18(1):100-10. Epub 2009 Nov 12.

We report here structural analysis of the interactions of TTR with two small molecules, 1-amino-5-naphthalene sulfonate (1,5-AmNS) and 1-anilino-8-naphthalene sulfonate (1,8-ANS).
2(0,0,0,2) Details