| Name | U87 |
|---|---|
| Synonyms | HBII 276; U87; SNORD87 |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18032788 | Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB: Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive species. J Cell Sci. 2007 Dec 1;120(Pt 23):4155-66. Herein, we determined that inhibitors of complex I (rotenone) and complex II (TTFA) induce cell death and autophagy in the transformed cell line HEK 293, and in cancer cell lines U87 and HeLa. |
31(0,1,1,1) | Details |
| 16678157 | Lai JS, Zhao C, Warsh JJ, Li PP: Cytoprotection by lithium and varies between cell types and cellular stresses. Eur J Pharmacol. 2006 Jun 6;539(1-2):18-26. Epub 2006 Apr 5. In the present study, we investigated whether lithium and at clinically relevant doses, protects human neuroblastoma (SH-SY5Y) and glioma (SVG and U87) cells against oxidative stress and endoplasmic reticulum stress in a time-dependent manner. Pretreatment of SH-SY5Y cells for 7 days, but not 1 day, with 1 mM of lithium or 0.6 mM of significantly reduced rotenone and H2O2-induced cytotoxicity, cytochrome c release and caspase-3 activation, and increased Bcl-2 levels. |
1(0,0,0,1) | Details |