| 12220540 |
Belyaeva EA, Glazunov VV, Korotkov SM: Cyclosporin A-sensitive permeability transition pore is involved in Cd (2+)-induced dysfunction of isolated rat liver mitochondria: doubts no more. Arch Biochem Biophys. 2002 Sep 15;405(2):252-64.
Sustained activation by low [Cd (2+)] of mitochondrial basal respiration in KCl medium is observed both in the absence and in the presence of rotenone and/or oligomycin but only in the latter case (rotenone+oligomycin) CsA inhibits completely Cd (2+) activation of St 4 respiration and partially reverses DNP-uncoupled respiration depressed by cadmium. |
81(1,1,1,1) |
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