Protein Information

Name CREB
Synonyms Active transcription factor CREB; CREB; CREB 1; CREB1; cAMP response element binding protein; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP responsive element binding protein 1 isoform B…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
15897899 Felty Q, Singh KP, Roy D: Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling. Oncogene. 2005 Jul 21;24(31):4883-93.

Furthermore, E2-induced binding of AP-1 and CREB to the TRE and CRE response sequences, respectively, in the promoter of cyclin D1 was inhibited by NAC or rotenone.
31(0,1,1,1) Details
19861415 Chowanadisai W, Bauerly KA, Tchaparian E, Wong A, Cortopassi GA, Rucker RB: Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. J Biol Chem. 2010 Jan 1;285(1):142-52. Epub 2009 Oct 27.

Moreover, PQQ protected cells from mitochondrial inhibition by rotenone, 3-nitropropionic acid, antimycin A, and sodium azide.
3(0,0,0,3) Details