| Name | ATPase is |
|---|---|
| Synonyms | ATP11A; Cation transporting ATPase; ATPIH; ATPIS; ATPase Class VI type 11A; ATPase IS; ATPase class I type 11A; Phospholipid translocating ATPase… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14638429 | Palese LL, Gaballo A, Technikova-Dobrova Z, Labonia N, Abbrescia A, Scacco S, Micelli L, Papa S: Characterization of plasma membrane respiratory chain and ATPase in the actinomycete Nonomuraea sp. FEMS Microbiol Lett. 2003 Nov 21;228(2):233-9. The respiratory chain is made up of a rotenone-sensitive -quinone oxidoreductase, a four subunits aa3-type cytochrome c oxidase and a bc1 complex. The H+-ATPase is characterized as an F0F1-type on the basis of its sensitivity to specific inhibitors; the enzyme is also inhibited by mM concentrations of Ca2+. |
1(0,0,0,1) | Details |
| 7370008 | Scott ID, Nicholls DG: Energy transduction in intact synaptosomes. Biochem J. 1980 Jan 15;186(1):21-33. Even under control conditions the plasma membrane (Na+ + K+)-dependent ATPase is responsible for a significant proportion of the synaptosomal ATP turnover. The addition of rotenone to inhibit respiration does not affect the plasma membrane potential, and only lowers the mitochondrial membrane potential to 128mV. |
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| 15843467 | Feldkamp T, Kribben A, Weinberg JM: F1FO-ATPase activity and ATP dependence of mitochondrial energization in proximal tubules after hypoxia/reoxygenation. J Am Soc Nephrol. 2005 Jun;16(6):1742-51. Epub 2005 Apr 20. In these studies, the mechanisms for the decreased DeltaPsi (m) in the tubules after H/R are further investigated and impairment of the function of the mitochondrial F (1) F (O)-ATPase is assessed. Normoxic control tubules had a small ATP-dependent component to DeltaPsi (m), but it required low micromolar levels of ATP, not the millimolar levels needed to support DeltaPsi (m) in tubules de-energized with rotenone or after H/R. |
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| 1260063 | Babitch JA, Breithaupt TB, Chiu TC, Garadi R, Helseth DL: Preparation of chick brain synaptosomes and synaptosomal membranes. . Biochim Biophys Acta. 1976 Apr 16;433(1):75-89. Purity of the subcellular and subsynaptosomal fractions was monitored by electron microscopy and measurements of ferrocytochrome c: oxidoreductase (EC 1.9.3.)), monoamine: oxidoreductase (deaminating) EC 1.4.3.4), rotenone-insensitive cytochrome c oxidoreductase (EC 1.6.99.3), cytochrome c oxidoreductase (EC 1.6.99.1), orthophosphoric monoester phosphohydrolase (EC 3.1.3.2), ATP phosphohydrolase (EC 3.6.1.4), and levels of RNA. Marker enzymes for contaminants suggest that these synaptosomal membranes are as pure as membranes described by others, and the specific activity of a neuronal membrane marker, (Na+ -K+)-activated ATPase, is as high as other preparations. |
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