Protein Information

Name 24 kDa protein
Synonyms 1 Cys PRX; PRDX 6; PRDX6; 1 Cys; 1 Cys peroxiredoxin; 24 kDa protein; AOP 2; AOP2…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
10491161 Almeida T, Duarte M, Melo AM, Videira A: The 24-kDa iron-sulphur subunit of complex I is required for enzyme activity. Eur J Biochem. 1999 Oct 1;265(1):86-93.

The gene was inactivated in vivo by repeat-induced point-mutations, and mutant strains lacking the 24-kDa protein were isolated.
In agreement with this, the respiration of intact mitochondria or mitochondrial membranes from the mutant strain is insensitive to rotenone inhibition.
2(0,0,0,2) Details