Protein Information

Name gamma tubulin (protein family or complex)
Synonyms Gamma tubulin; Gamma tubulin complex; Gamma tubulins

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
15893636 Diaz-Corrales FJ, Asanuma M, Miyazaki I, Miyoshi K, Ogawa N: Rotenone induces aggregation of gamma-tubulin protein and subsequent disorganization of the centrosome: relevance to formation of inclusion bodies and neurodegeneration. Neuroscience. 2005;133(1):117-35.
12(0,0,2,2) Details
18083626 Johnson GE, Parry EM: Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone. Mutat Res. 2008 Mar 12;651(1-2):56-63. Epub 2007 Nov 12.

For a mechanistic evaluation of the aneugenic effects of BPA and rotenone, fluorescently labelled antibodies were used to visualise microtubules (alpha-tubulin) and MTOCs (gamma-tubulin).
6(0,0,1,1) Details
11724769 Lee HJ, Shin SY, Choi C, Lee YH, Lee SJ: Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors. J Biol Chem. 2002 Feb 15;277(7):5411-7. Epub 2001 Nov 27.

Treatment with rotenone, an inhibitor of complex I, resulted in an increase of detergent-resistant alpha-synuclein aggregates and a reduction in ATP level.
The inclusions were co-stained with ubiquitin, 20 S proteasome, gamma-tubulin, and vimentin.
1(0,0,0,1) Details