| Name | dynamin (protein family or complex) |
|---|---|
| Synonyms | Dynamin; Dynamins |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15024001 | Frieden M, James D, Castelbou C, Danckaert A, Martinou JC, Demaurex N: Ca (2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1. J Biol Chem. 2004 May 21;279(21):22704-14. Epub 2004 Mar 15. To study the effect of a controlled disruption of the mitochondrial network on Ca (2+) homeostasis, we took advantage of hFis1, a protein that promotes mitochondrial fission by recruiting the dynamin-related protein, Drp1. hFis1 expression in HeLa cells induced a rapid and complete fragmentation of mitochondria, which redistributed away from the plasma membrane and clustered around the nucleus. Regardless of mitochondria shape and location, disruption of mitochondrial potential with uncouplers or oligomycin/rotenone reduced CCE by approximately 35%. |
1(0,0,0,1) | Details |
| 16624952 | Jiang Q, Yan Z, Feng J: Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. J Neurosci. 2006 Apr 19;26(16):4318-28. We found that L-AP-4 induced a rapid and transient activation of the MAP kinase extracellular signal-regulated kinase (ERK) through a pathway mediated by dynamin, beta-arrestin 2, and Src. |
1(0,0,0,1) | Details |
| 16874299 | Barsoum MJ, Yuan H, Gerencser AA, Liot G, Kushnareva Y, Graber S, Kovacs I, Lee WD, Waggoner J, Cui J, White AD, Bossy B, Martinou JC, Youle RJ, Lipton SA, Ellisman MH, Perkins GA, Bossy-Wetzel E: -induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J. 2006 Aug 23;25(16):3900-11. Epub 2006 Jul 27. Mitofusin 1 (Mfn1) or dominant-negative Dynamin related protein 1 (Drp1 (K38A)) inhibits mitochondrial fission induced by NO, rotenone and Amyloid-beta peptide. |
1(0,0,0,1) | Details |