| Name | calcineurin inhibitor |
|---|---|
| Synonyms | CABIN 1; CAIN; CABIN1; Calcineurin binding protein 1; Calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin binding protein 1s; Calcineurin binding protein cabin 1s… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15280438 | Watabe M, Nakaki T: Rotenone induces apoptosis via activation of bad in human dopaminergic SH-SY5Y cells. J Pharmacol Exp Ther. 2004 Dec;311(3):948-53. Epub 2004 Jul 27. Because dephosphorylation by calcineurin activates Bad, we examined the possible involvement of Bad activation in rotenone-induced apoptosis by using the calcineurin inhibitor tacrolimus (FK506). |
81(1,1,1,1) | Details |
| 19492085 | Sandebring A, Thomas KJ, Beilina A, van der Brug M, Cleland MM, Ahmad R, Miller DW, Zambrano I, Cowburn RF, Behbahani H, Cedazo-Minguez A, Cookson MR: Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. PLoS One. 2009 May 27;4(5):e5701. We also show that wild-type PINK1, but not recessive mutant or kinase dead versions, protects against rotenone-induced mitochondrial fragmentation whereas PINK1 deficient cells show lower mitochondrial connectivity. |
0(0,0,0,0) | Details |