| Name | voltage dependent anion channel |
|---|---|
| Synonyms | VDAC3; VDAC3; VDAC5P; Voltage dependent anion channel; Voltage dependent anion channels |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7983042 | Pastorino JG, Simbula G, Gilfor E, Hoek JB, Farber JL: an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone. J Biol Chem. 1994 Dec 9;269(49):31041-6. The association of the PBzR with the voltage-dependent anion channel of the outer mitochondrial membrane and with the nucleotide carrier of the inner membrane suggests that this complex mediates the transport of PPIX across the mitochondrial membranes. |
2(0,0,0,2) | Details |
| 18802751 | Xiong Y, Ding H, Xu M, Gao J: Protective effects of asiatic acid on rotenone- or H2O2-induced injury in SH-SY5Y cells. Neurochem Res. 2009 Apr;34(4):746-54. Epub 2008 Sep 19. Mitochondrial membrane potential (MMP) and the expression of voltage-dependent anion channel (VDAC) were detected with or without AA pretreatment following cellular injury to address the possible mechanisms of AA neuroprotection. |
1(0,0,0,1) | Details |
| 15686486 | Clayton R, Clark JB, Sharpe M: Cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit: implications for apoptosis and neurodegenerative disease. J Neurochem. 2005 Feb;92(4):840-9. Titration of rat brain mitochondrial respiratory function, with the specific complex I inhibitor rotenone, caused proportional release of cytochrome c from isolated synaptic and non-synaptic mitochondria. The mechanism of release was mediated, at least in part, by the mitochondrial outer membrane component Bak and voltage-dependent anion channel rather than non-specific membrane rupture. |
1(0,0,0,1) | Details |
| 10816428 | Doran E, Halestrap AP: Cytochrome c release from isolated rat liver mitochondria can occur independently of outer-membrane rupture: possible role of contact sites. Biochem J. 2000 Jun 1;348 Pt 2:343-50. Dextran also inhibited both mitochondrial oxidation of exogenous ferrocytochrome c in the presence of rotenone and antimycin, and respiratory-chain-driven reduction of exogenous ferricytochrome c. Polyaspartate, which stabilizes the low conductance state of the voltage-dependent anion channel (VDAC), increased cytochrome c release. |
1(0,0,0,1) | Details |