| Name | tyrosine kinase receptor |
|---|---|
| Synonyms | 55 kd protein; MTC; High affinity nerve growth factor receptor; High affinity nerve growth factor receptor precursor; NTRK 1; NTRK1; Neurotrophic tyrosine kinase receptor type 1; Oncogene tyrosine protein kinase receptor… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10854229 | Mandriota SJ, Pyke C, Di Sanza C, Quinodoz P, Pittet B, Pepper MS: Hypoxia-inducible angiopoietin-2 expression is mimicked by iodonium compounds and occurs in the rat brain and skin in response to systemic hypoxia and tissue ischemia. Am J Pathol. 2000 Jun;156(6):2077-89. Angiopoietins are ligands for the endothelial cell tyrosine kinase receptor Tie-2. Neither Ang-2 or VEGF was increased by or rotenone, suggesting that failure in mitochondrial electron transport is not involved in the -sensing system that controls their expression. |
1(0,0,0,1) | Details |
| 17555550 | Hirata Y, Kiuchi K: Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins. J Neurochem. 2007 Sep;102(5):1606-13. Epub 2007 Jun 7. Treatment of mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine caused decreases in levels of Ret, a tyrosine kinase receptor for glial cell line-derived neurotrophic factor (GDNF) in the striatum, under the condition in which tyrosine hydroxylase was moderately decreased and the GDNF family receptor alpha1, another receptor of GDNF that is the ligand-binding subunit, were unaffected. Down-regulation of Ret was also observed in -producing PC12 cells undergoing apoptosis induced by rotenone, another toxic substance for dopaminergic neurons, while other cellular components were not affected. |
1(0,0,0,1) | Details |
| 16778190 | Kim YM, Kim KE, Koh GY, Ho YS, Lee KJ: peroxide produced by angiopoietin-1 mediates angiogenesis. Cancer Res. 2006 Jun 15;66(12):6167-74. We found that human umbilical vein endothelial cells treated with Ang1 produce ROS transiently, which was suppressed by oxidase inhibitor, diphenylene-iodonium and rotenone. |
0(0,0,0,0) | Details |
| 17029596 | Hirata Y, Meguro T, Kiuchi K: Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis. J Neurochem. 2006 Oct;99(2):416-25. Both rotenone and are possible neurotoxins for a wide variety of cell and neuronal types including dopaminergic neurons and induce apoptosis in various cells. |
0(0,0,0,0) | Details |