| Name | PDX1 |
|---|---|
| Synonyms | DLDBP; PDX1; Dihydrolipoamide dehydrogenase binding protein of pyruvate dehydrogenase complex; E3 binding protein; E3BP; Lipoyl containing pyruvate dehydrogenase complex component X; OPDX; PDHX… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15151993 | Gauthier BR, Brun T, Sarret EJ, Ishihara H, Schaad O, Descombes P, Wollheim CB: Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets. J Biol Chem. 2004 Jul 23;279(30):31121-30. Epub 2004 May 19. Rotenone, an inhibitor of complex I, mimicked this effect. |
4(0,0,0,4) | Details |
| 14607783 | Peterside IE, Selak MA, Simmons RA: Impaired oxidative phosphorylation in hepatic mitochondria in growth-retarded rats. Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1258-66. Increased levels of manganese superoxide dismutase suggest that an antioxidant response has been mounted, and hydroxynonenal (HNE) modification of pyruvate dehydrogenase E2-(catalytic) and E3-binding protein subunits suggests that HNE-induced inactivation of this key enzyme may play a role in the mechanism of injury. Rotenone-sensitive -O2 oxidoreductase activity was similar in control and IUGR mitochondria at all ages, showing that the defect responsible for decreased and alpha-ketoglutarate oxidation in IUGR liver precedes the electron transport chain and involves and alpha-ketoglutarate dehydrogenases. |
1(0,0,0,1) | Details |
| 17254815 | Vellucci VF, Gygax SE, Hostetter MK: Involvement of Candida albicans pyruvate dehydrogenase complex protein X (Pdx1) in filamentation. Fungal Genet Biol. 2007 Oct;44(10):979-90. Epub 2006 Dec 16. In basal salts medium with < or = 100 mM as carbon source, two independent pdx1 mutants displayed a filamentation defect identical to ndh51; reintegration of one PDX1 allele restored filamentation. |
1(0,0,0,1) | Details |