Protein Information

Name MT 2
Synonyms CES 1; CES1; MT 2A; MT II; MT IIa; MT 2; MT2; MT2A…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
16402917 Reinecke F, Levanets O, Olivier Y, Louw R, Semete B, Grobler A, Hidalgo J, Smeitink J, Olckers A, Van der Westhuizen FH: Metallothionein isoform 2A expression is inducible and protects against ROS-mediated cell death in rotenone-treated HeLa cells. Biochem J. 2006 Apr 15;395(2):405-15.

MT2A overexpression in rotenone-treated cells also significantly reduced or delayed apoptosis induction, as measured by caspase 3/7 activity and cytosolic nucleosome enrichment.
45(0,1,3,5) Details
19781773 Ito S, Oyake T, Murai K, Ishida Y: Deguelin suppresses cell proliferation via the inhibition of survivin expression and STAT3 phosphorylation in HTLV-1-transformed T cells. Leuk Res. 2010 Mar;34(3):352-7. Epub 2009 Sep 24.


We examined the effect of deguelin, a naturally occurring rotenoid, on HTLV-1-transformed T-cell lines, KUT-1 and MT-2 cells.
1(0,0,0,1) Details