Name | estrogen related receptor alpha |
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Synonyms | ERR alpha; ERR 1; ERR1; ERRa; ERRalpha; ESRL 1; ESRL1; ESRRA… |
Name | chlordane |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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16515477 | Ariazi EA, Jordan VC: receptors as emerging targets in cancer and metabolic disorders. Curr Top Med Chem. 2006;6(3):203-15. The organochlorine pesticides toxaphene and chlordane, and the synthetic compound XCT790 antagonize ERRalpha. |
-related 84(1,1,1,4) | Details |
20351196 | Miao L, Shi J, Wang CY, Zhu Y, Du X, Jiao H, Mo Z, Klocker H, Lee C, Zhang J: Estrogen Receptor-Related Receptor {alpha} Mediates Up-Regulation of Aromatase Expression by in Prostate Stromal Cells. Mol Endocrinol. 2010 Mar 29. Estrogen receptor-related receptor alpha (ERRalpha) is an orphan member of the nuclear receptor superfamily of transcription factors. Suppression of ERRalpha activity by chlordane (an antagonist of ERRalpha) or small interfering RNA knockdown of ERRalpha blocked the increase of expression and promoter activity of aromatase induced by |
9(0,0,0,9) | Details |
18646811 | Jin KS, Park JK, Yoon J, Rho Y, Kim JH, Kim EE, Ree M: Small-angle X-ray scattering studies on structures of an estrogen-related receptor alpha ligand binding domain and its complexes with ligands and coactivators. J Phys Chem B. 2008 Aug 14;112(32):9603-12. Epub 2008 Jul 23. We tested 4-hydroxytamoxifen, diethylstilbestrol, chlordane, daidzein, and as ligands. |
2(0,0,0,2) | Details |
10493499 | Yang C, Chen S: Two organochlorine pesticides, toxaphene and chlordane, are antagonists for estrogen-related receptor alpha-1 orphan receptor. Cancer Res. 1999 Sep 15;59(18):4519-24. |
2(0,0,0,2) | Details |
11850205 | Chen S, Zhou D, Yang C, Okubo T, Kinoshita Y, Yu B, Kao YC, Itoh T: Modulation of aromatase expression in human breast tissue. J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):35-40. The modulation of aromatase expression by endocrine disrupting chemicals is exemplified by two organochlorine pesticides (i.e. toxaphene and chlordane) that have been found to be antagonists of ERRalpha-1 orphan receptor. |
83(1,1,1,3) | Details |