| Name | serotonin transporter |
|---|---|
| Synonyms | Sodium dependent serotonin transporter; OCD1; 5 hydroxytryptamine transporter; 5HT transporter; 5HTT; HTT; OCD 1; SERT… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19358877 | Savitz JB, Drevets WC: Imaging phenotypes of major depressive disorder: genetic correlates. Neuroscience. 2009 Nov 24;164(1):300-30. Epub 2009 Apr 7. Hippocampal volume loss is characteristic of elderly or chronically-ill samples and may be impacted by the val66met brain-derived neurotrophic factor (BDNF) gene variant and the 5-HTTLPR SLC6A4 polymorphism. |
2(0,0,0,2) | Details |
| 20090673 | Holmes AJ, Bogdan R, Pizzagalli DA: Serotonin transporter genotype and action monitoring dysfunction: a possible substrate underlying increased vulnerability to depression. Neuropsychopharmacology. 2010 Apr;35(5):1186-97. Epub 2010 Jan 20. |
2(0,0,0,2) | Details |
| 18261931 | Passamonti L, Cerasa A, Gioia MC, Magariello A, Muglia M, Quattrone A, Fera F: Genetically dependent modulation of serotonergic inactivation in the human prefrontal cortex. Neuroimage. 2008 Apr 15;40(3):1264-73. Epub 2007 Dec 27. Although with conflicting findings, the monoamine oxidase-A (MAOA) and the serotonin transporter (5HTT) gene polymorphisms have been associated with an increased risk to develop impulsive and aggressive behaviour. |
1(0,0,0,1) | Details |
| 19944766 | Meda SA, Jagannathan K, Gelernter J, Calhoun VD, Liu J, Stevens MC, Pearlson GD: A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia. Neuroimage. 2009 Nov 26. The fMRI components, along with their significant genetic profile (dominant SNP) correlations were as follows: (1) Inferior frontal-anterior/posterior cingulate-thalamus-caudate with SNPs from Brain derived neurotropic factor (BDNF) and dopamine transporter (DAT) [r=-0.51; p <0.0001], (2) superior/middle temporal gyrus-cingulate-premotor with SLC6A4_PR and SLC6A4_PR_AG (serotonin transporter promoter; 5HTTLPR) [r=0.27; p=0.03], and (3) default mode-fronto-temporal gyrus with Brain derived neurotropic factor and dopamine transporter (BDNF, DAT) [r=-0.25; p=0.04]. |
1(0,0,0,1) | Details |