Protein Information

Name calcitonin gene related peptide
Synonyms Alpha type CGRP; CT; CGRP; CALC 1; CALC1; CALCA; CGRP 1; CGRP I…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
7540981 Lo YC, Wu SN, Wu JR, Chen IJ: Effect of capsaicin on membrane currents in cultured vascular smooth muscle cells of rat aorta. Eur J Pharmacol. 1995 Mar 16;292(3-4):321-8.

Capsaicin inhibited the Ba2+ inward current (IBa) through the voltage-dependent L-type Ca2+ channel in a concentration-dependent fashion, whereas calcitonin gene-related peptide and phenylephrine produced a minor increase in IBa.
31(0,1,1,1) Details
16549032 Morikawa T, Matsuzawa Y, Makita K, Katayama Y: Antimigraine drug, zolmitriptan, inhibits high-voltage activated calcium currents in a population of acutely dissociated rat trigeminal sensory neurons. Mol Pain. 2006 Mar 20;2:10.

Zolmitriptan (0.1-100 microM) reduced the size of IBa in a concentration-dependent manner.
CONCLUSION: It is concluded that this zolmitriptan inhibition of HVA Ca (2+) channels may explain the reduction in the release of neurotransmitters including CGRP, possibly leading to antimigraine effects of zolmitriptan.
1(0,0,0,1) Details
6472529 Mori H, Iba K, Nishizawa Y, Okamoto T, Matsushita Y, Kikunami K, Inoue T, Inoue T: Abnormal calcium metabolism in hemodialyzed patients with diabetic nephropathy. Nephron. 1984;38(1):22-5.


Serum calcitonin was higher in HD/DM than that in HD/non-DM.
1(0,0,0,1) Details