Protein Information

Name Ca v
Synonyms CA V; CA VA; CA5; CA5A; CAV; CAVA; Carbonate dehydratase VA; Carbonic anhydrase V…

Compound Information

Name allethrin
CAS 2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate

Reference List

PubMed Abstract RScore(About this table)
14634047 Hildebrand ME, McRory JE, Snutch TP, Stea A: Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin. J Pharmacol Exp Ther. 2004 Mar;308(3):805-13. Epub 2003 Nov 21.

Allethrin caused blockade with IC (50) values of 7.0 microM for T-type alpha (1G) (Ca (v) 3.1), 6.8 microM for L-type alpha (1C) (Ca (v) 1.2), and 6.7 microM for P/Q-type alpha (1A) (Ca (v) 2.1) channels.
81(1,1,1,1) Details