Protein Information

Name IgE
Synonyms IGHE; Ig epsilon chain C region; IgE; immunoglobulin heavy constant epsilon; Ig epsilon chain C regions; IgEs; immunoglobulin heavy constant epsilons

Compound Information

Name bioallethrin
CAS

Reference List

PubMed Abstract RScore(About this table)
9860237 Diel F, Detscher M, Schock B, Ennis M: In vitro effects of the pyrethroid S-bioallethrin on lymphocytes and basophils from atopic and nonatopic subjects. Allergy. 1998 Nov;53(11):1052-9.

The inhibition of the lymphocyte proliferation by S-bioallethrin at the concentration 6.5 microM correlated well with the total serum IgE values (r = -0.89, P < 0.001).
37(0,1,2,2) Details
10414782 Diel F, Horr B, Borck H, Savtchenko H, Mitsche T, Diel E: Pyrethroids and piperonyl-butoxide affect human T-lymphocytes in vitro. Toxicol Lett. 1999 Jun 30;107(1-3):65-74.

Although this effect was little compared to histamine liberators like FMLP and anti-IgE, the response to S-bioallethrin and PBO was significantly different in atopic donors compared with non-atopics (P < 0.01).
6(0,0,1,1) Details
12755381 Diel F, Horr B, Borck H, Irman-Florjanc T: Pyrethroid insecticides influence the signal transduction in T helper lymphocytes from atopic and nonatopic subjects. Inflamm Res. 2003 Apr;52(4):154-63.

Only fenvalerate and S-bioallethrin combined with 10-fold PBO in the atopic-enriched blood basophil incubates caused a weak but significant increase in histamine release.
MATERIAL AND METHODS: PHA-stimulated cultures of T-helper lymphocytes and blood basophil incubates from nonatopic and atopic patients (IgE > 1000 IU) provided cytokine and histamine determination.
1(0,0,0,1) Details