Protein Information

Name NF E2 related factor 2
Synonyms HEBP 1; HEBP1; NF E2 related factor 2; NFE2 related factor 2; NFE2 related trancription factor 2; NFE2L2; NRF 2; NRF2…

Compound Information

Name deltamethrin
CAS

Reference List

PubMed Abstract RScore(About this table)
17676812 Li HY, Zhong YF, Wu SY, Shi N: NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells. Chem Res Toxicol. 2007 Sep;20(9):1242-51. Epub 2007 Aug 4.
82(1,1,1,2) Details
16737586 Li HY, Shi N, Dai ZH, Zhong YF, Wu SY: [Effects of deltamethrin on gene expression of some antioxidase, gamma glutamylcysteine synthetase and NFE2 related factor 2 (Nrf2) in brain tissue]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006 May;24(5):273-7.
12(0,0,2,2) Details
16758951 Li HY, Shi N, Zhong YF, Dai ZH: [Time course of gene expression of gamma-glutamylcysteine synthetase subunit and Nrf2 in brain tissues of rats exposed by deltamethrin]. Wei Sheng Yan Jiu. 2006 Mar;35(2):130-4.

OBJECTIVE: To investigate the time course of mRNA expression of gamma- glutamylcysteine synthetase light (GCSl) and heavy subunit (GCSh), as well as protein expression of both GCSh and NF-E2 related factor 2 (Nrf2) in cerebral cortex and hippocampus in rats exposed at single dose of deltamethrin (DM).
6(0,0,1,1) Details
17540521 Li HY, Wu SY, Shi N: Transcription factor Nrf2 activation by deltamethrin in PC12 cells: Involvement of ROS. Toxicol Lett. 2007 Jun 15;171(1-2):87-98. Epub 2007 Apr 27.

Activation of transcription factor NF-E2-related factor 2 (Nrf2) is a key initiation step in the cellular protection against a broad range of chemical oxidative stresses.
1(0,0,0,1) Details