| Name | Ca v |
|---|---|
| Synonyms | CA V; CA VA; CA5; CA5A; CAV; CAVA; Carbonate dehydratase VA; Carbonic anhydrase V… |
| Name | deltamethrin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17294162 | Clark JM, Symington SB: Pyrethroid action on channels: neurotoxicological implications. Invert Neurosci. 2007 Mar;7(1):3-16. Epub 2007 Feb 9. Deltamethrin (10 (-7) M) reduced the peak current (approx. -47%) of heterologously expressed wild type Ca (v) 2.2 in a stereospecific manner. |
199(2,3,4,4) | Details |
| 18383452 | Clark JM, Symington SB: implications of the agonistic action of CS-syndrome pyrethroids on the N-type Ca (v) 2.2 calcium channel. Pest Manag Sci. 2008 Jun;64(6):628-38. Deltamethrin reduced peak current of heterologously expressed wild-type Ca (v) 2.2, increased peak current of T422E Ca (v) 2.2 and was 20-fold more potent on T422E Ca (v) 2.2 than on wild-type channels, indicating that the permanently phosphorylated form of Ca (v) 2.2 is the preferred target. |
164(2,2,2,4) | Details |
| 16678970 | Wu ZZ, Chen SR, Pan HL: Signaling mechanisms of down-regulation of voltage-activated Ca2+ channels by transient receptor potential vanilloid type 1 stimulation with olvanil in primary sensory neurons. Neuroscience. 2006 Aug 11;141(1):407-19. Epub 2006 May 6. Furthermore, calcineurin (protein phosphatase 2B) inhibitors (deltamethrin and FK-506) eliminated the effect of olvanil on voltage-activated Ca (2+) channel current. In addition, double immunofluorescence labeling revealed that olvanil induced a rapid internalization of Ca (V) 2.2 immunoreactivity from the membrane surface of dorsal root ganglion neurons. |
1(0,0,0,1) | Details |
| 15746091 | Wu ZZ, Chen SR, Pan HL: Transient receptor potential vanilloid type 1 activation down-regulates voltage-gated channels through -dependent calcineurin in sensory neurons. J Biol Chem. 2005 May 6;280(18):18142-51. Epub 2005 Mar 3. Furthermore, intracellular dialysis of deltamethrin or cyclosporin A, the specific calcineurin (protein phosphatase 2B) inhibitors, but not okadaic acid (a selective protein phosphatase 1/protein phosphatase 2A inhibitor), abolished the effect of on I (Ca). Immunofluorescence labeling revealed that induced a rapid internalization of Ca (V) 2.2 channels on the membrane. |
1(0,0,0,1) | Details |