Protein Information

Name sodium channel (protein family or complex)
Synonyms Sodium channel

Compound Information

Name phenothrin
CAS (3-phenoxyphenyl)methyl 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate

Reference List

PubMed Abstract RScore(About this table)
14680113 Tomita T, Yaguchi N, Mihara M, Takahashi M, Agui N, Kasai S: Molecular analysis of a para sodium channel gene from pyrethroid-resistant head lice, Pediculus humanus capitis (Anoplura: Pediculidae). J Med Entomol. 2003 Jul;40(4):468-74.

Phenothrin-susceptible and -resistant head louse colonies from Japanese were individually analyzed for point mutations of the sodium channel cDNA; susceptible head and body lice differed in double homozygous synonymous substitutions.
9(0,0,1,4) Details
2449265 Ruigt GS, Neyt HC, Van der Zalm JM, Van den Bercken J: Increase of sodium current after pyrethroid insecticides in mouse neuroblastoma cells. Brain Res. 1987 Dec 29;437(2):309-22.

The effects of 4 different pyrethroid insecticides on sodium channel gating in internally perfused, cultured mouse neuroblastoma cells (N1E-115) were studied using the suction pipette, voltage clamp technique.
The rate of decay of the slow tail current strongly depended on pyrethroid structure and increased in the order deltamethrin, cyphenothrin, fenfluthrin and phenothrin.
1(0,0,0,1) Details